Protein Purification
MilliporeSigma™ Calbiochem™ AG 1295
A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500nM) and PDGF-dependent DNA synthesis (IC50 = 2.5μM) in Swiss/3T3 cells.
MilliporeSigma™ Calbiochem™ STAT3 Inhibitor III, WP1066
STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent.
MilliporeSigma™ Calbiochem™ Thrombin Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of thrombin.
MilliporeSigma™ Calbiochem™ SB 242084 Hydrochloride
A selective, brain-penetrant 5-HT2C receptor antagonist (pK
MilliporeSigma™ Calbiochem™ TRPM Antagonist, M8-An
A cell-permeable, readily bioavailable 2-picolinamide derivative that acts as a highly potent antagonist of transient receptor potential cation channel subfamily M member 8 (TRPM8; IC50 =
MilliporeSigma™ Calbiochem™ Protein Synthesis Initiation Inhibitor, NSC 119889
The Protein Synthesis Initiation Inhibitor, NSC 119889 blocks 5'-mediated/cap-dependent initiation of protein synthesis. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ RGS Proteins Inhibitor II, CCG-50014
The RGS Proteins Inhibitor II, CCG-50014 controls the biological activity of RGS4 proteins. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal
4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation.
MilliporeSigma™ Calbiochem™ Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride
A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki =
MilliporeSigma™ Calbiochem™ Nocodazole
Inhibitor of mitosis.
MilliporeSigma™ Calbiochem™ Tpl2 Kinase Inhibitor
The Tpl2 Kinase Inhibitor, also referenced under CAS 871307-18-5, controls the biological activity of Tpl2 Kinase.
MilliporeSigma™ Calbiochem™ PERK Inhibitor I, GSK2606414
GSK2606414 is a cell-permeable, highly potent inhibitor of EIF2AK3/PERK (IC50 = 0.4 nM; [ATP] = 5 μM). Targets PERK in its inactive DFG conformation at the ATP-binding region.
MilliporeSigma™ Calbiochem™ SIRT1 Inhibitor IV, (S)-35
The SIRT1 Inhibitor IV, (S)-35, also referenced under CAS 848193-72-6, controls the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ AG 490
A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100 nM).
MilliporeSigma™ Calbiochem™ RAF Kinase Inhibitor VII
A cell-permeable imidazopyridinyl-urea compound that acts as a potent inhibitor against B-RafV600E activity (IC50 = 1nM) by targeting its ATP-binding pocket and the adjacent lipophilic allosteric site accessible only when the enzyme is in its inactive DFG-out confor